Molgramostim: Recombinant Human GM-CSF

Molgramostim is indeed the generic name for a drug that is a recombinant form of human granulocyte-macrophage colony-stimulating factor (GM-CSF). It is also commonly referred to as “recombinant human GM-CSF.” The drug is used to stimulate the production of white blood cells in the bone marrow.

GM-CSF is a naturally occurring protein in the body that plays a crucial role in the growth and maturation of white blood cells, including granulocytes and macrophages. By administering recombinant human GM-CSF, it is possible to enhance the production of these immune cells, which can be beneficial in various medical scenarios.

Molgramostim is approved for use in certain medical conditions, such as:

  1. Reconstitution of bone marrow after bone marrow transplantation.
  2. Treatment of certain cases of bone marrow failure or decreased bone marrow function.
  3. Mobilization of hematopoietic progenitor cells (stem cells) from the bone marrow to the peripheral blood for stem cell transplantation.
  4. Treatment of severe chronic neutropenia, a condition characterized by abnormally low levels of neutrophils (a type of white blood cell).
  5. Acceleration of recovery of white blood cell counts after chemotherapy or bone marrow transplantation.


It’s essential to note that Molgramostim should be used under the supervision of a qualified healthcare professional, and its use is specific to particular medical conditions as determined by the treating physician. As with any medication, it may have potential side effects or interactions with other drugs, so patients should be closely monitored during treatment.

Key Features:
  1. Superior Quality: AffiREC® Molgramostim is manufactured using advanced recombinant DNA technology and stringent quality control processes. This ensures a highly pure and biologically active GM-CSF product with consistent performance and minimal lot-to-lot variability.
  2. Stimulates Hematopoietic Cells: As a potent hematopoietic growth factor, Molgramostim plays a crucial role in the proliferation, differentiation, and activation of granulocytes and macrophages. It promotes the development of various myeloid cell lineages, contributing to immune response regulation, hematopoiesis, and tissue repair processes.
  3. Versatile Applications: AffiREC® Molgramostim finds broad applications in immunology, oncology, vaccine development, and regenerative medicine. It is utilized in studies investigating the modulation of immune cell function, therapeutic approaches targeting myeloid cells, and the development of innovative immunotherapies.
  4. Research Advancements: AffiREC® Molgramostim empowers researchers to delve into the complex mechanisms underlying hematopoiesis, immune system regulation, and the development of targeted therapies. It enables in-depth investigations into the role of GM-CSF in various disease models and provides valuable insights for drug discovery and development.
  5. Reliable Support: AffiGen is committed to providing exceptional customer support and scientific expertise. Our team of experts is readily available to assist with product selection, technical inquiries, and guidance on experimental design and optimization.

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